Is it safe to take nyquil with benadryl

NSAIDs (non-steroidal anti-inflammatory drugs) and analgesics. acetaminophen (Tylenol) aspirin (Bayer’s) ibuprofen (Advil/Motrin) naproxen (Naprosyn) Advil PM, Tylenol PM. (Most “PM” medications contain diphenhydramine) Most OTC pain meds are safe to fly as long as the underlying condition is acceptable. Aches and Pains.

Is it safe to take nyquil with benadryl. A doctor has provided 1 answer. nyquil makes me really sick to my stomach.... what do i do? im sick and need sleep: Try Benadryl (diphenhydramine): Most nyquil preparations contain dextr.

Metoprolol is a generic prescription medication approved by the U.S. Food and Drug Administration (FDA). It is classified as a beta-blocker (in the same drug class as medications such as propranolol and atenolol) and works by relaxing blood vessels and slowing the heart rate to lower blood pressure and improve blood flow. Metoprolol may …

Which allergy medications are safe to take with high blood pressure, and which ones are not. Learn how Benadryl, as well as other common allergy medications, affect blood pressure. Conditions A-ZApplies to: Benadryl (diphenhydramine) and ZzzQuil (diphenhydramine) Ask your doctor before using diphenhydrAMINE together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental ...Is it safe to take nyquil simultaneously with pain reliever? A doctor has provided 1 answer. i have the flu before surgery in 2 days and i was wondering if i could take any medication that wouldnt affect the surgery like nyquil ?: Moot point: situation may be a moot point as many surgeons might not w.Mucinex and NyQuil are both products that relieve symptoms of the common cold or flu. The symptoms they treat are different. You can take Mucinex and NyQuil together safely if you follow the ...Call your doctor or 911 if you think you may have a medical emergency. Yes tho dont need to: Nyquil has an antihistamine so really no added benefit to both it and Benadryl (diphenhydramine) at the same time.Long-term side effects. Over-the-counter (OTC) Benadryl is approved for temporary or short-term use and is not intended for long-term use. There is very little scientific research about the long ...

Antihistamines are considered safe to use. They are used for a wide range of symptoms including post nasal drip, congestion, and allergy symptoms. Claritin, Zyrtec, and Allegra all last 24 hours and are good options to combine with Wellbutrin if needed. While most antihistamines are considered safe with Wellbutrin, one exception may be Benadryl.The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ...If you’re wondering whether it’s safe to take Benadryl and Nyquil together, let me provide some insights. Both medications are commonly used for different purposes; Benadryl is an antihistamine that helps with allergies, while Nyquil is a cold and flu relief medication.While effective, the risk of serious diphenhydramine side effects—including confusion, dizziness, urinary retention, and liver or kidney issues—is increased in people age 65 and older. This article explores how diphenhydramine works, potential side effects, and why it's generally recommended that older adults avoid using diphenhydramine ...NyQuil already contains doxylamine, which is almost exactly like Benadryl (diphenhydramine), so it wouldn't be a good idea to take them together since that would be a "duplication of therapy".

Apr 11, 2018 ... Benadryl and NyQuil Zzz have the same active ingredient (Diphenhydramine HCL), they're just marketed for different purposes.Can You Take Nyquil And Benadryl Together. When you’re feeling under the weather, it’s natural to reach for over-the-counter remedies like Nyquil and Benadryl. However, is it safe to take these two together? The answer isn’t as straightforward as you might think. Nyquil, a popular cold and flu medicine, contains ingredients that help ...While there is no interaction between NyQuil and phentermine, they do have conflicting effects. Phentermine can have amphetamine-like effects and is a CNS (central nervous system) stimulant. These effects include: Increased concentration. Increased attentiveness. Restlessness. Over-stimulation. NyQuil contains doxylamine, a sedating antihistamine.How Benadryl makes sleeping easier. Antihistamines stop allergic reactions by blocking excess production of histamine in the immune system. Some also block histamine release in the brain. The ...The main one for antihistamines is drowsiness, so it can be tough to take during the day. That's why they're often included in nighttime cold medicines. Other common side effects include dry mouth ...

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The fetus should be OK. "Most women who take NyQuil for a short period of time in pregnancy will not have any adverse outcomes in pregnancy," Dr. Langan says. "We advise against taking it out of ...Certain medications cannot be taken together, such as combining Benadryl and NyQuil. Since ibuprofen works differently than acetaminophen - the pain-relieving component in NyQuil - it is generally considered safe to take Advil and NyQuil together for short-term use. More about this combination below…. Just make sure you follow the ...Melatonin is a hormone that regulates the body's circadian rhythm (the sleep-wake cycle). It's also available as a dietary supplement. Like Benadryl, it's often used for sleep disturbances like insomnia (trouble falling or staying asleep). There's some controversy over whether these two medicines are safe to take together.Maximum dose: 50mg. Motion sickness: 25mg to 50mg up to three or four times a day as needed. Maximum: 300 mg/day. Note that these dosages are for adults who are otherwise healthy and are on no interacting medicines. The dosage of diphenhydramine may need reducing in those with certain medical conditions or taking certain medicines.Take OTC antihistamines; Antihistamines dry up mucous membranes of the nose and other areas such as mouth and eyes. Nasal decongestant sprays, such as oxymetazoline (Afrin, Vick's Sinex) and phenylephrine (Neo-Synephrine), can also be helpful. Related Questions. What is the Benadryl hat man? Can you overdose on Nyquil?Question: Are stable-value funds a safe investment? —Rexford, Syracuse, New York Answer: That depends on what you mean by safe. Stable-value funds, which are available… By c...

Moving a gun safe can require special equipment. We break down the best gun safe movers in your area. Expert Advice On Improving Your Home Videos Latest View All Guides Latest View...Decongestants can pose a risk to people living with a thyroid disorder, such as an overactive thyroid ( hyperthyroidism) or an underactive thyroid ( hypothyroidism ). This is because ingredients like pseudoephedrine can affect the blood vessels throughout the body. Some drugs may interact with your thyroid medication.Allegra D 12 Hour Allergy and Congestion: pseudoephedrine and fexofenadine. Alka-Seltzer Plus Flu: aspirin, chlorpheniramine, and dextromethorphan. Benadryl Allergy and Cold: acetaminophen, diphenhydramine, and phenylephrine. Children's Dimetapp Cold and Cough: brompheniramine, dextromethorphan, and phenylephrine.NyQuil can become addictive. It's also possible to develop an addiction to NyQuil, per The Recovery Village. If you get in the habit of taking it every night, it will stop having the same effect. When your tolerance increases, it will likely take longer to fall asleep and you may find yourself waking up rather than sleeping through the night.However, Benadryl can also cause dry mouth, constipation, and urinary retention. Nyquil can cause drowsiness, dizziness, and nausea. Benadryl and Nyquil are both safe to take during pregnancy. Benadryl and Nyquil are both safe to take for children, but it is important to follow the dosage instructions carefully.No, you shouldn't take NyQuil and ZzzQuil at the same time. Both NyQuil and ZzzQuil contain a sedative antihistamine - Diphenhydramine . If you take the meds together at the same time, you will end up overdosing on Diphenhydramine and the most concerning side effect would be excess sedation. NyQuil does contain other active ingredients ...When trying to reduce their fevers some people take cold showers or an ice bath. But that has the opposite effect. “Do not use an ice bath or cold. It will make the fever go up,” said Whitley ...Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies.Dana Benson. 713-798-8267. Houston, TX - Jun 28, 2021. Share this article. For people who take an antihistamine such as Benadryl for a cold or allergies, drowsiness is often a welcome side effect. But a Baylor College of Medicine sleep expert cautions against turning to this type of medication as a sleep aid.Benadryl (diphenhydramine) cetirizine; Claritin (loratadine) Fish Oil (omega-3 polyunsaturated fatty acids) gabapentin; ibuprofen; levothyroxine; lisinopril; losartan; ... Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction ...Answer. Benadryl (diphenhydramine), Ambien (zolpidem), and melatonin are not recommended to be taken together due to additive sedation and additive CNS depression. The resulting side effects could be dangerous. Two or more of these medications should only be taken together under the recommendation and supervision of your doctor.Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect... View more. Prescription and OTC. Prescribed for Anaphylaxis, Allergic Reactions, Oral Allergy Syndrome.

Key points. Taking NyQuil products, which contain the sedating antihistamine doxylamine, with melatonin can increase sedation and have additive CNS depressant effects. There are a variety of Nyquil products currently available over-the-counter, but most contain the following active ingredients: Acetaminophen. Dextromethorphan.

Requirements for Safe Houses - Safe houses come in different types: defensive and offensive. But what are the requirements that define an effective safe house? Advertisement A safe...6 doctors weighed in across 2 answers. Dr. Andrew Oswari answered. Specializes in Family Medicine. Be careful: Some people do mix these medicines in order to get to sleep, but this not a good idea without consulting your primary. The main reaction is sedation, so you should never operate machinery while taking these together.Answer. It is generally not recommended to take promethazine with codeine and NyQuil together, for numerous reasons.. Both Drugs Contain Antihistamines. First and foremost, NyQuil contains the antihistamine doxylamine, which is similar to Benadryl in that it is classified as a sedating "first-generation" antihistamine.. Promethazine is also an antihistamine, with very similar effects to ...Applies to: Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine) and mirtazapine. Using doxylamine together with mirtazapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking ...Pseudoephedrine (Sudafed) is an oral decongestant used to treat nasal congestion. It's kept behind the counter at the pharmacy. Pseudoephedrine can interact with medications that affect the brain. These include tricyclic antidepressants (TCAs), some types of headache medications, and caffeine. It's best to avoid interactions with ...Therefore, it takes about 52 to 65 hours to get all the ingredients from this NyQuil product out of your system. Elimination of drugs from your body can vary, based on your kidney or liver function, age, weight, hydration or other factors. Acetaminophen has a half-life of about 1.25 to 3 hours, doxylamine is 10 hours, and alcohol is 4 to 5 hours.Both medications contain diphenhydramine as their active ingredient. Taking Nyquil and Benadryl together can potentially increase the diphenhydramine level in your system beyond what is considered safe. Excessive amounts of diphenhydramine can lead to side effects such as drowsiness, dizziness, blurred vision, dry mouth, and constipation.No, you should not take Benadryl and Xanax together. Taking Xanax and Benadryl together can intensify side effects like dizziness, fatigue, drowsiness, inability to. concentrate, and lack of coordination. Combining the two can be especially dangerous for the elderly. Like many drug reactions, the effects of either medication can be intensified ...

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Diphenhydramine (Benadryl, Advil PM, others). Doxylamine (NyQuil Cold & Flu, Nighttime Cold & Flu Relief, others). Chlorpheniramine (Chlor-Trimeton, Alka-Seltzer Plus Cold Medicine, others). Antihistamines that make you sleepy can be useful as a sleep aid once in a while. But tolerance to the effects of these antihistamines develops quickly.Answer. There is no known drug interaction between azithromycin (Z-Pak) and Nyquil (acetaminophen, dextromethorphan, and doxylamine). They can be safely taken together. 'NyQuil Severe', which contains one additional ingredient when compared to the 'original' NyQuil, is also safe to take with a Z-Pak. Below, I discuss each medication in more detail.While effective, the risk of serious diphenhydramine side effects—including confusion, dizziness, urinary retention, and liver or kidney issues—is increased in people age 65 and older. This article explores how diphenhydramine works, potential side effects, and why it's generally recommended that older adults avoid using diphenhydramine ...Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people. The most common side effects of diphenhydramine include: drowsiness. dizziness. loss of ...Benadryl is an over-the-counter (OTC) syrup commonly used by people to alleviate the symptoms of cough or as an antihistamine to improve the symptoms of skin irritation. However, maintain caution as Benadryl while breastfeeding may be unsafe as it has mild sedative properties and may pass into the baby through the breastmilk.Certain medications cannot be taken together, such as combining Benadryl and NyQuil. Since ibuprofen works differently than acetaminophen - the pain-relieving component in NyQuil - it is generally considered safe to take Advil and NyQuil together for short-term use. More about this combination below…. Just make sure you follow the ...Each dose of NyQuil (30 ml or two tablespoons) contains 30 mg of dextromethorphan. Doxylamine: Doxylamine is a sedating "first generation" antihistamine and is the component of NyQuil (in addition to the alcohol), that causes drowsiness. It also is an effective antihistamine and can help reduce itchy, watery eyes, chest congestion and post ...Applies to: Benadryl (diphenhydramine) and ZzzQuil (diphenhydramine) Ask your doctor before using diphenhydrAMINE together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental ...Sold as a liquid or a liquid-filled capsule, ZzzQuil is a sleep aid that is used to treat insomnia characterized by difficulty falling or staying asleep. ZzzQuil is meant to relieve occasional sleeplessness, and shouldn't be used for insomnia lasting more than two weeks. If insomnia is affecting your daily life, such as feeling exhausted most ... ….

Decongestants can pose a risk to people living with a thyroid disorder, such as an overactive thyroid ( hyperthyroidism) or an underactive thyroid ( hypothyroidism ). This is because ingredients like pseudoephedrine can affect the blood vessels throughout the body. Some drugs may interact with your thyroid medication.50 mg. 100 mg. The typical hydroxyzine dosage for adults with insomnia is 50 mg daily, taken at least 30 minutes before bedtime. Your healthcare provider will recommend the appropriate dosage based on your condition. Meanwhile, Benadryl has two doses—25 mg and 50 mg. The average dose of Benadryl for sleep issues is 50 mg daily, taken orally.Best Mobility Tips & Devices for Getting Around Your Home and Outside Click below for information on safe and convenient transportation and mobility options for seniors: Featured P...diphenhydrAMINE oxyCODONE. Applies to: Benadryl (diphenhydramine) and oxycodone. Using diphenhydrAMINE together with oxyCODONE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.There is no reported or listed interaction between Nyquil and omeprazole (brand name Prilosec). They are considered to be safe to take together. Having said that, one of the ingredients in Nyquil may exacerbate symptoms of heartburn and acid reflux. Nyquil And Acid Reflux. Nyquil contains the following ingredients: Acetaminophen …But a 2015 Consumer Reports national survey of 4,023 adults found a troubling trend: Of the 20 percent who took an OTC medication within the past year to improve sleep, almost 1 in 5 respondents ...Decongestants can pose a risk to people living with a thyroid disorder, such as an overactive thyroid ( hyperthyroidism) or an underactive thyroid ( hypothyroidism ). This is because ingredients like pseudoephedrine can affect the blood vessels throughout the body. Some drugs may interact with your thyroid medication.Many search engines offer a safe search filter, which simply means that explicit search results like websites containing sexual content are filtered from appearing in your search r...Topline. Some of the most common cold medications like Benadryl, Mucinex and variations of Tylenol may soon be forced off shelves after a Food and Drug Administration panel found oral ... Is it safe to take nyquil with benadryl, Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies., Amoxicillin is available in doses of 250 mg, 500 mg and 1 g. These are administered in different combinations depending upon the clinical condition. Amoxicillin is used as a 500 mg oral or intravenous drug. In treating simple pneumonias, amoxicillin is prescribed as a 500 mg oral medication given 2 to 3 times a day for a variable duration of time depending upon the severity of infection., Assuming 1 Doxylamine pill is one dosage and you took 2, then you took 4 times the maximum amount of anticholinergic antihistamines that should be taken at once, not only that they will likely synergise to increase the effects of each other. You will probably at least experience restlessness leg syndrome., Tylenol can be taken on its own, but there are many multi-symptom cold & flu remedies that also contain acetaminophen as an active ingredient. These include: Alka-Seltzer Plus Cold & Flu. Contac Cold + Flu. Coricidin HBP Cold & Flu. Equate Cold & Flu Multi-Symptom Relief. Mucines Cold & Flu. Robitussin Multi-Symptom Cough Cold + Flu., Applies to: Vicks NyQuil Cold & Flu Nighttime Relief (Alcohol Free) (acetaminophen / chlorpheniramine / dextromethorphan) and oxycodone. Using chlorpheniramine together with oxyCODONE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience ... , Not a good idea: Effexor (venlafaxine) should be taken in the morning to improve depression, increase mental energy, and to prevent insomnia. If you take NyQuil because you cannot sleep, you might benefiting from the 25-50 mg of diphenhydramine (Benadryl) on it., NyQuil is a cough syrup used to treat respiratory ailments in dogs for years. While it may seem like a solution to your dog's cold, you should never give it to them because it can be toxic to dogs. If your dog ingests enough of it, it can cause seizures, liver damage, and even death. It can be tempting to think NyQuil will help because it ..., Tony asked. I take Abilify daily and am always concerned about drug interactions. Is it safe to take Abilify with Benadryl? Answer. The use of Abilify (aripiprazole) and Benadryl (diphenhydramine) may require monitoring as there is a moderate drug interaction between these two medications.. There are actually two potential interactions between Abilify and Benadryl:, Benadryl is better at treating most allergy symptoms, such as runny nose and sneezing. Mucinex may be helpful if your allergies are causing a cough from postnasal drip. Mucinex has very few side effects. Benadryl often causes drowsiness, dry mouth, and constipation. You can take Mucinex and Benadryl at the same time if you need to., Tamiflu can be taken with over-the-counter (OTC) cold and flu medications, such as NyQuil products. It's also safe to take Tamiflu with OTC pain relievers, such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). ... Can you take Tamiflu and Benadryl together? Yes, most people can take Tamiflu and Benadryl (diphenhydramine) together., Common side effects may include: dizziness, drowsiness, loss of coordination; dry mouth, nose, or throat; constipation, upset stomach; dry eyes, blurred vision; or. day-time drowsiness or "hangover" feeling after night-time use. This is not a complete list of side effects and others may occur., Dec 27, 2022 · No, NyQuil does not contain Benadryl (diphenhydramine). NyQuil contains the following medications: Acetaminophen: An analgesic used for the treatment of fever, headache, aches, and pains. Dextromethorphan: An antitussive agent to help control cough. Doxylamine: A first-generation antihistamine that is commonly used as a sleeping agent due to ... , Benadryl is a "first-generation" antihistamine used to treat allergic reactions, and it is also commonly used as a sleep aid for patients who are having difficulty falling asleep. Benadryl is generally well tolerated but has significant sedative effects, which is why it is a common ingredient in sleep aids. It can also cause:, Many people wonder if they can take Benadryl and Nyquil together, especially when dealing with cold or allergy symptoms. Both medications are commonly used to relieve symptoms such as sneezing, runny nose, and itchy eyes. However, it is important to understand the potential risks and interactions before combining these two drugs., Mar 7, 2024 ... Drug interactions are reported among 126 peopel who take Nyquil and Benadryl. Common interactions among females include metabolic alkalosis ..., In regard to NyQuil and Sudafed (pseudoephedrine), they can safely be taken together as NyQuil does not already contain a decongestant and there are no interactions between any of the drugs. You can also take one in the morning and one in the evening as you suggested. The 'original' NyQuil contains the following ingredients:, No laws exist that prevent you from keeping cash in a safe deposit box. However, while not illegal, bankers typically discourage customers from keeping cash in safe deposit boxes b..., Common side effects of NyQuil include constipation, appetite loss, anxiousness, stomach upset and queasiness, according to Drugs.com. Severe side effects include urinary difficulti..., More about ZzzQuil ( diphenhydramine ) Ratings & Reviews. Benadryl has an average rating of 7.3 out of 10 from a total of 78 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. ZzzQuil has an average rating of 2.7 out of 10 from a total of 67 ratings on Drugs.com. 16% of reviewers reported a ..., NyQuil contains several sedating ingredients, including alcohol (10% by volume) and doxylamine, a first-generation antihistamine. NyQuil technically can be taken during the day, but remember that it will make you tired. Generally, it is best to only take it at night or if you plan on being home during the day resting., This is why Benadryl and related antihistamines (e.g. doxylamine) are used in over the counter sleep aid products like NyQuil and ZzzQuil. Going back to using Benadryl for congestion, there are several published studies that have evaluated how well antihistamines like Benadryl work for congestion., Can a person take nyquil 8 hours before having liver,kidney,bilirubin blood tests and gallbladder test such as ct scan ,x ray ? A doctor has provided 1 answer. A member asked: How is nyquil bad for your body? A doctor has provided 1 answer. A member asked:, Benadryl (diphenhydramine) Bystolic (nebivolol) CoQ10 (ubiquinone) Crestor (rosuvastatin) Cymbalta (duloxetine) Eliquis (apixaban) ... Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available., Each dose of NyQuil (30 ml or two tablespoons) contains 30 mg of dextromethorphan. Doxylamine: Doxylamine is a sedating "first generation" antihistamine and is the component of NyQuil (in addition to the alcohol), that causes drowsiness. It also is an effective antihistamine and can help reduce itchy, watery eyes, chest congestion and post ..., According to WebMD, there are no drug interactions between Tylenol and Benadryl, so they can be taken at the same time. However, a personal doctor or pharmacist should always be in..., Answer. The use of Abilify (aripiprazole) and Benadryl (diphenhydramine) may require monitoring as there is a moderate drug interaction between these two medications. There are actually two potential interactions between Abilify and Benadryl: Both can cause CNS (central nervous system) depression and can cause additive …, Pain and Fever Reducers. Pain relievers and fever reducers that are safe to take while breastfeeding include: Tylenol (acetaminophen) Advil, Motrin (ibuprofen) Aleve (naproxen) Acetaminophen and NSAIDs (ibuprofen, naproxen) can be taken together. However, avoid taking more than one NSAID or more than one product containing …, Answer. There is no known drug interaction between azithromycin (Z-Pak) and Nyquil (acetaminophen, dextromethorphan, and doxylamine). They can be safely taken together. 'NyQuil Severe', which contains one additional ingredient when compared to the 'original' NyQuil, is also safe to take with a Z-Pak. Below, I discuss each medication in more detail., Certain medications cannot be taken together, such as combining Benadryl and NyQuil. Since ibuprofen works differently than acetaminophen – the pain-relieving component in NyQuil – it is generally considered safe to take Advil and NyQuil together for short-term use. More about this combination below…. Just make sure you follow the ..., NyQuil is a popular brand of over-the-counter (OTC) cough and cold products. Not all NyQuil products are safe for children under 12 years old. The recommended NyQuil dosage for kids ages 6 to 11 years old is 15 mL by mouth every 4 or 6 hours, depending on which product you choose. No more than 4 doses of any NyQuil product should be given in 24 ..., This can be dangerous if the medicine is accidentally rubbed into the eye. Fluoxetine (Prozac), paroxetine (Paxil), amitriptyline (Elavil), Tofranil ( Imipramine) and duloxetine (Cymbalta) for depression or anxiety. Sulfa-containing drugs such as topiramate (Topamax) for seizures/migraine, acetazolamide (Diamox) or trimethoprim-sulfamethoxazole ..., Benadryl (diphenhydramine) is also a first-generation antihistamine that can cause sedation or drowsiness. It is considered to be in the same class of drugs as the doxylamine that is found in NyQuil. Benadryl can also be used as a short-term sleeping aid, but it is also commonly used to treat allergies, allergic reactions, and itching., Taking higher doses can put you at higher risk for negative side effects, Dr. Tallavajhula says, including dry mouth, dizziness and daytime grogginess. 3. You Could Have Rebound Insomnia. If you take Zzzquil for a while and then stop suddenly, your sleep problems will likely come back even worse than before, notes the Cleveland Clinic.